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The prognostic factors

The prognostic factors related because the degree of tumor invasion and lymph growth transparietal and the facts or absence of metastases were included supremacy the classifications. The standard for post - therapeutic codification of cancers of the colon is represented by the classifications uiic - AJCC, Astler - Gum Dukes and the hang-up of which facilitates therapeutic outcome.

1 - Current Aligning UICC ( TNM ) and AJCC Primary tumor ( T ): - TX: tumor not assessable - TO: no tumor on the levy, - Tis: carcinoma significance situ - T1: way the submucosa, - T2: Achieving the Forceful - T3: achievement of the sub - serosa to serosa or fat pericoli, - T4: path the peritoneal cavity terminated the serosa or extension by contiguity to a section finished the serosa.
Regional lymphadenopathy ( N ): - NX: non - specific lymphadenopathy, - N0: no regional lymphadenopathy, - N1: 1 to 3 pericoli metastatic lymphadenopathy, - N2: 4 or expanded metastatic adenopathies pericoli, - N3: adenopathies central ( vascular trunks ) metastatic.

Remote metastases ( M ): - MX: not momentous - M0: no metastasis, - M1: metastases.
Residual tumor ( R ) ( AJCC ): - RO: berges resection microscopically for love of residual tumor, - R1: berges microscopically invaded resection, - R2: macroscopic residual tumor ( surgical findings ).

Grouping into stages: - Stage I: T1 N0M0, T2N0M0, - Stage II: T3 N0M0, T4 N0M0, - Stage III: lump T, N1, N2 or N3, M0, - Stage IV: slab T or N, M1.
2 - Structure of Dukes Sensible has been appropriate for colon cancer by Kirklin.

- Stage A: Achieving the mucosa or the submucosa and muscles lost striking the sub - serosa.
- Stage B: transparietal reached beyond the sub - serosa.

- Stage C: knob.
3 - Disposal of Astler - Paste ( modified Dukes ) Essential was useful by Turnbull to add the stage D ( spot invasion or metastasis ) [TURNBULL 1967].

- Stage A: infringement or mucosa submucosa.

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- Stage B1: achieving strength strayed stirring the sub - serosa.

- Stage B2: Achieving bodybuilding take cover achievement of the sub - serosa or serosa or beyond.
- Grounds C1: B1 keep from nodal.

- Field C2: B2 ensconce nodal.
- Stage D: metastases.

4 - Conjunction between Compound and Astler - TNM - A: T1N0M0 - B1: T2N0M0 - B2: T3N0M0, T4N0M0, - C1: T1N1 or N3M0 or N2, N2 or T2N1 or N3M0, - C2: T3N1 or N3M0 or N2, N2 or T4N1 or N3M0, - D: M1, whatever the T or N Treatment 1 - The total colonoscopy Colonoscopy is an exigent choice pull the treatment of colon cancer in that throughout the sickness restraint equate used at this mode. The examination extremity factor performed underneath anesthesia.
Ten polyp becoming cancerous, evident is accepted that all polyps should appear as removed. This removal is a function of its size: - Surgery to biopsy forceps - Removal to coadunate " torrid " - Polypectomy to handgrip diathermic Endoscopy has a limited niche: Endoscopy has assumed the diagnosis and showed the presence of polyps associated, allowing the surgeon to indicate the length of the resection. We will use it only in cases of colonic stenosis.

2 - Surgical treatment of uncomplicated cancers The treatment of localized colon cancer is surgical. It aims to colonic segmental excision of the primary tumor with margins of healthy colon and removal of various lymph nodes relay.
3 - Surgical treatment of complicated cancers The treatment will depend on the patient ' s general condition and location of the tumor. When the tumor invades the bodies of the neighborhood, the resection is done en bloc.

4 - Chemotherapy When complete resection is not possible, chemotherapy is the treatment of reference in a palliative. Two associations 5 - FU - AF ( level of evidence A ) and / or 5 - FU - MTX ( + / - AF ) ( level of evidence A ) have superior efficacy to 5 - FU administered as a single intravenous bolus in terms of response induced toxicity and only one ( 5 - FU - MTX + / - EF ) determining a statistically significant improvement in survival.

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The continuous intravenous infusion of 5 - FU ( level of evidence B ) or raltitrexed ( level of evidence C ) represent an option in view of comparable efficacy with the combination of 5 - FU - AF.

For cancers of the colon C stage, adjuvant chemotherapy is a standard ( level of evidence A ). Associations 5 - fluorouracil and folinic acid ( level of evidence A ) or 5 fluorouracil - levamisole are options ( level of evidence B ). For colon cancer Stage B, there is no standard for adjuvant treatment. The use of chemotherapy in stage B2 remains in the field of therapeutic trial.
FU: fluorouracil AF: folinic acid MTX: Methotrexate Levels of evidence described Level A: There is a study, meta - type " well done " or more clinical trials " well done " whose results are consistent.

Level B: there are studies, such clinical trials, quasi - experimental studies or comparisons of populations whose results are not consistent throughout.
Level C: There are studies, such clinical trials, quasi - experimental studies or comparisons of populations whose results are consistent throughout.

Level D: no data or only case - series.
Agreements experts: there is no data for the method in question but all the experts are unanimous For more information Descriptive Epidemiology of Colorectal Cancer Incidence of colorectal cancer - Epidemiology adenomas - Subjects at risk for colorectal cancer - References.

By Anne - Marie Bouvier - Benhamiche, Faculte de Medecine, 21033 Dijon Cedex. Word file, April 2001.
View the document Standards, Options and Recommendations for the management of patients with colon cancer The aim of these recommendations is to define, based on a review of scientific literature, recommendations for care diagnostic, therapeutic and monitoring after treatment of patients with colon cancer.

Abridged version available online in pdf format.
View the document Thesaurus colon cancer Diagnostic and pre - treatment - Treatment of colon cancer metastatic non - Treatment of metastatic colon cancer - Surveillance View the document Colon cancer Epidemiology - Anatomopathologie - Diagnosis - Change - Forecasting - Testing - Principles of treatment.

Natural colon cleansers are a complete colon treatment in itself. The product is safe to use and is made from natural herbal extracts and fiber rich psyllium. It has a multiiaction formula, which not only cleanses the colon tract but also detoxifies your body organs. You don’t have to worry about your diet. Just have anything and you will be free of parasites and other bacterial collection. Colon cleanser will give you slim and healthy looks and when you go out the next time, you don’t have to worry about your loosely hanging flab. The ideal health product is all designed to boost your energy levels to new echelons. And why not, when your internal body system is working well you have everything working fine on your side.

Handout of Gastroenterology. By Professor PH Cugnenc of Broussais Hospital View the document Prevention, Detection and Management of Colon Cancer Summary of responses of consensus led by the French National Society of Gastroenterology and the National Federation of Centers for the Fight against Cancer: Primary prevention of colorectal cancer is possible? Screening for colon cancer is it possible and useful? What are the explorations useful diagnostic and therapeutic decision? What are the standards of curative treatment? What to do after curative surgery for colon cancer? What treatment proposed in locally advanced colon cancer and / or metastatic? PDF, 1998.
View the document Prevention, detection and treatment of cancers of the colon Primary prevention of colorectal cancer is possible? Screening for colon cancer is it possible and useful? What are the explorations useful diagnostic and therapeutic decision? What are the standards of curative treatment? What to do after curative surgery for colon cancer? What treatment proposed in locally advanced colon cancer and / or metastatic?

Consensus conference - January 1998.
Topics and oncology.

View the document Colorectal cancer Circumstances of discovery, diagnosis, assessment of extension treatment.
Corpus Medical Consultation - By J. Fournet - September 1997 View the document Videoscopie Images and video service Gastroenterology CHU de Rennes, 2 rue Henri Le Guilloux, 35033 Rennes Cedex.: Normal colon, colon cancer stenosis, bleeding colon cancer, villous tumor of the cecum, colon diverticula... By Laurent Siproudhis, proctologue doctor at the University Hospital of Rennes.

View the document Guides to good practice ( English ) Adjuvant Therapy for Stage II Colon Cancer Following Complete Resection ( Practice Guideline No. 2 - 1 ) View the document Adjuvant Therapy for Stage III Colon Cancer Following Complete Resection ( Practice Guideline No. 2 - 2 ) View the document Use of Raltitrexed ( Tomudex ) in the Management of Metastatic Colorectal Cancer ( Practice Guideline No. 2 - 17 ) View the document Recommended Colorectal Cancer Surveillance Guidelines by the American Society of Clinical Oncology View the document Colonoscopy in the Screening and Surveillance of Individuals at Increased Risk for Colorectal Cancer View the document

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